2006 and 2007 250cc World Champion, and the 2010, 2012 and 2015 MotoGP World Champion. He currently competes in the MotoGP class, riding for Honda. He rode for Yamaha from 2008 to 2016. On 6 June 2018 it was announced Lorenzo would be joining the Repsol Honda team for the 2019 and 2020 MotoGP seasons. Apart from his three titles in the premier class, Lorenzo has also finished as runner-up on three occasions. In 2012, Lorenzo became the first Spanish rider to win multiple premier class titles, and with 67 career wins, he is sixth on the all-time wins list.
In 2017 season, Lorenzo switched team from Yamaha to Ducati. he scored three podiums and finished seventh in the overall standings.
After yet another difficult season opening blighted by a brake failure in Qatar and a collision while fighting for a podium at Jerez, Lorenzo took his first Ducati victory in the Italian round at Mugello with a dominant lights-to-flag performance. This was Lorenzo's sixth win at the particular circuit and broke his longest MotoGP winless streak up until that date. Remarkably, Lorenzo followed this up with a dominant win at the Circuit de Catalunya, his first back to back wins in MotoGP since 2016.
Lorenzo's third win for the 2018 season came in Austria.